The combination of kavalactones (described above) are what create the calming effects of kava root. There are about 18 kavalactones that we know about. Six of these kavalactones provide the majority of those active ingredients. The combined mixture of kavalactones, from strongest to weakest is called the Chemotype. Different varieties of kava have different chemotypes. Further, the stump and the lateral roots will typically have different chemotypes. Which means a prepared kava beverage from two different parts of the plant will produce different effects. Some chemotype mixes are more uplifting and great for drinking in the daytime. Others are fantastic for drinking in the nighttime and used as a sleep aid.